FONDATION

Hunter-gatherer diets - a different perspective: Katharine Milton; Am J Clin Nutr, 2000, 71:665–7

Hunter-Gatherer Energetics and Human Obesity: Herman Pontzer, David A. Raichlen, Brian M. Wood, Audax Z. P. Mabulla, Susan B. Racette, Frank W. Marlowe; PLoS One. 2012, 7(7)

Comparison with ancestral diets suggests dense acellular carbohydrates promote an inflammatory microbiota, and may be the primary dietary cause of leptin resistance and obesity: Ian Spreadbury; Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 2012, 5 175–189

Energy expenditure and activity among Hadza hunter-gatherers: Herman Pontzer, David A. Raichlen, Brian M. Wood, Melissa Emery Thompson, Susan B. Racette, Audax Z.P. Mabulla andFrank W. Marlowe; Am J Hum Biol, 2015, doi: 10.1002/ajhb.22711

Insulin, Leptin and Reward: Jon F. Davis, Derrick L. Choi, and Stephen C. Benoit; Trends Endocrinol Metab, 2010, 21(2):68

Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK–SIRT1-PGC-1α pathway: Mary D. L. Chau, Jiaping Gao, Qing Yang, Zhidan Wu, and Jesper Gromada; PNAS, 2010, vol. 107, no. 28

Regulation of Energy Balance and Body Weight by the Brain: A Distributed System Prone to Disruption: Lucy F. Faulconbridge and Matthew R. Hayes; Psychiatr Clin North Am, 2011, 34(4): 733–745.

Long-Term Persistence of Hormonal Adaptations to Weight Loss: Priya Sumithran, Luke A. Prendergast, Elizabeth Delbridge, Katrina Purcell, Arthur Shulkes, Adamandia Kriketos and Joseph Proietto; N Engl J Med, 2011, 365:1597-604

Hedonic and incentive signals for body weight control: Emil Egecioglu, Karolina P. Skibicka, Caroline Hansson, Mayte Alvarez-Crespo, P. Anders Friberg, Elisabet Jerlhag, Jörgen A. Engel and Suzanne L. Dickson; Rev Endocr Metab Disord, 2011, 12:141–151

Influence of Running and Walking on Hormonal Regulators of Appetite in Women: D. Enette Larson-Meyer, Sonnie Palm, Aasthaa Bansal, Kathleen J. Austin, Ann Marie Hart and Brenda M. Alexander; J Obes, 2012, Article ID 730409

Obesity and Appetite Control: Keisuke Suzuki, Channa N. Jayasena, and Stephen R. Bloom; Exp Diabetes Res, 2012, doi:10.1155/2012/824305

Brain Regulation of energy balance and body weights: Liangyou Rui; Rev Endocr Metab Disord, 2013, 14(4)

Role of Appetite-Regulating Peptides in the Pathophysiology of Addiction: Implications for Pharmacotherapy: Jörgen A. Engel and Elisabet Jerlhag; CNS Drugs, 2014, 28:875–886

Hypothalamic and brainstem neuronal circuits controlling homeostatic energy balance: Marc Schneeberger, Ramon Gomis and Marc Claret; J Endocrinol, 2014, 220, T25-T46

Effects of high-fructose diets on central appetite signaling and cognitive function: Katrien Lowette, Lina Roosen, Jan Tack and Pieter Vanden Berghe; Front Nutr, 2015, 2, 5:1-5

Alternate-day fasting in nonobese subjects: effects on body weight, body composition, and energy metabolism: Leonie K Heilbronn, Steven R Smith, Corby K Martin, Stephen D Anton and Eric Ravussin; Am J Clin Nutr, 2005, 81:69–73

Prolonged fasting in patients with chronic pain syndromes leads to late mood-enhancement not related to weight loss and fasting-induced leptin depletion. Michalsen A, Kuhlmann MK, Lüdtke R, Bäcker M, Langhorst J, Dobos GJ; Nutr Neurosci, 2006, 9(5-6):195-200

Alternate Day Calorie Restriction Improves Clinical Findings and Reduces Markers of Oxidative Stress and Inflammation in Overweight Adults with Moderate Asthma: James B. Johnson, Warren Summer, Roy G. Cutler, Bronwen Martin, Dong-Hoon Hyun, Vishwa D. Dixit, Michelle Pearson, Matthew Nassar, Stuart Maudsley, Olga Carlson, Sujit John, Donald R. Laub and Mark P. Mattson; Free Radic Biol Med, 2007, 42(5): 665–674

Short-term low calorie diet intervention reduces serum advanced glycation end products in healthy overweight or obese adults. Gugliucci A, Kotani K, Taing J, Matsuoka Y, Sano Y, Yoshimura M, Egawa K, Horikawa C, Kitagawa Y, Kiso Y, Kimura S, Sakane N; Ann Nutr Metab, 2009, 54(3):197-201

Unkontrollierte klinische Studie zur Wirksamkeit ambulanten Heilfastens bei Patienten mit Arthrose: Schmidt S, Stange R, Lischka E, Kiehntopf M, Deufel T, Loth D und Uhlemann C; Forsch Komplementmed, 2010, 17:87–94

Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol: E. L. Lim, K. G. Hollingsworth, B. S. Aribisala, M. J. Chen, J. C. Mathers, R. Taylor; Diabetologia, 2011, 54(10):2506-14

The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women: M N Harvie, M Pegington, M P Mattson, J Frystyk, B Dillon, G Evans, J Cuzick, S A Jebb, B Martin, R G Cutler, T G Son, S Maudsley, O D Carlson, J M Egan, A Flyvbjerg and A Howell; Int J Obes (Lond), 2011, 35, 714-727

Intermittent fasting combined with calorie restriction is effective for weight loss and cardio-protection in obese women: Monica C Klempel, Cynthia M Kroeger, Surabhi Bhutani, John F Trepanowski and Krista A Varady; Nutr J, 2012, 11:98

The effect of intermittent energy and carbohydrate restriction v. daily energy restriction on weight loss and metabolic disease risk markers in overweight women: Michelle Harvie, Claire Wright, Mary Pegington, Debbie McMullan, Ellen Mitchell, Bronwen Martin, Roy G. Cutler, Gareth Evans, Sigrid Whiteside, Stuart Maudsley, Simonetta Camandola, Rui Wang, Olga D. Carlson, Josephine M. Egan, Mark P. Mattson and Anthony Howell; Br J Nutr, 2013, 110, 1534–1547

Alternate day fasting (ADF) with a high-fat diet produces similar weight loss and cardio-protection as ADF with a low-fat diet. Klempel MC, Kroeger CM and Varady KA; Metabolism, 2013, 62(1):137-43

The Effects of Intermittent Energy Restriction on Indices of Cardiometabolic Health: Rona Antoni, Kelly L. Johnston, Adam L. Collins and M. Denise Robertson; Research in Endocrinology, 2014, Article ID 459119

Safety of alternate day fasting and effect on disordered eating behaviors: Kristin K Hoddy, Cynthia M Kroeger, John F Trepanowski, Adrienne R Barnosky, Surabhi Bhutani and Krista A Varady; Nutr J, 2015, 14:44

Effects of weight loss via high fat vs. low fat alternate day fasting diets on free fatty acid profiles: Krista A. Varady, Vi T. Dam, Monica C. Klempel, Matthew Horne, Rani Cruz, Cynthia M. Kroeger and Sylvia Santosa; Sci Rep, 2015, 5;5:7561

Restoring normoglycaemia by use of a very low calorie diet in long- and short-duration Type 2 diabetes: Steven S, Taylor R; Diabet Med, 2015, doi: 10.1111/dme.12722

Practicality of intermittent fasting in humans and its effect on oxidative stress and genes related to aging and metabolism. Wegman MP, Guo MH, Bennion DM, Shanker MN, Chrzanowski SM, Goldberg LA, Xu J, Williams TA, Lu X, Hsu SI, Anton SD, Leeuwenburgh C and Brantly ML; Rejuvenation Res, 2015, 18(2):162-72

Fasting and Cancer Treatment in Humans: A Case series report: Fernando M. Safdie, Tanya Dorff, David Quinn, Luigi Fontana, Min Wei, Changhan Lee, Pinchas Cohen and Valter D. Longo; AGING, 2009, Vol.1 No.12

Fasting and differential chemotherapy protection in patients: Lizzia Raffaghello, Fernando Safdie, Giovanna Bianchi, Tanya Dorff, Luigi Fontana and Valter D. Longo; Cell Cycle, 2010,9:22, 4474-4476

Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy: Changhan Lee, Lizzia Raffaghello, Sebastian Brandhorst, Fernando M. Safdie, Giovanna Bianchi, Alejandro Martin-Montalvo, Vito Pistoia, Min Wei, Saewon Hwang, Annalisa Merlino, Laura Emionite, Rafael de Cabo and Valter D. Longo; Sci Transl Med, 2012, 4(124)

Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition: Irene Caffa, Vito D’Agostino, Patrizia Damonte, Debora Soncini, Michele Cea, Fiammetta Monacelli, Patrizio Odetti, Alberto Ballestrero, Alessandro Provenzani, Valter D. Longo and Alessio Nencioni; Oncotarget, 2015, Vol. 6, No. 14

Fasting cycles potentiate the efficacy of gemcitabine treatment in in vitro and in vivo pancreatic cancer models: Martina D’Aronzo, Manlio Vinciguerra, Tommaso Mazza, Concetta Panebianco, Chiara Saracino, Stephen P. Pereira, Paolo Graziano and Valerio Pazienza; Oncotarget, 2015, Vol. 6, No. 21

Treatment of periodontal disease results in improvements in endothelial dysfunction and reduction of the carotid intima-media thickness. Piconi S, Trabattoni D, Luraghi C, Perilli E, Borelli M, Pacei M, Rizzardini G, Lattuada A, Bray DH, Catalano M, Sparaco A, Clerici M; FASEB, 2009, J 23, 1196-1204

Human oral, gut, and plaque microbiota in patients with atherosclerosis: Omry Koren, Aymé Spor, Jenny Felin, Frida Fåk, Jesse Stombaugh, Valentina Tremaroli, Carl Johan Behre, Rob Knight, Björn Fagerberg, Ruth E. Ley and Fredrik Bäckhed; PNAS, 2011, vol. 108, suppl. 1, 4592–4598

The mind-body-microbial continuum: Antonio Gonzalez, Jesse Stombaugh, Catherine Lozupone, Peter J. Turnbaugh, Jeffrey I. Gordon and Rob Knight; Dialogues Clin Neurosci, 2011, 13:55-62

Gut microbiota and sirtuins in obesity-related inflammation and bowel dysfunction: Shaheen E Lakhan and Annette Kirchgessner; J Transl Med, 2011, 9:202

Sequencing ancient calcified dental plaque shows changes in oral microbiota with dietary shifts of the Neolithic and Industrial revolutions: Christina J Adler, Keith Dobney, Laura S Weyrich, John Kaidonis, Alan W Walker, Wolfgang Haak, Corey JA Bradshaw, Grant Townsend, Arkadiusz Sołtysiak, Kurt W Alt, Julian Parkhill and Alan Cooper; Nat Genet, 2013, 45(4): 450–455

The Human Gut Microbiome and Body Metabolism: Implications for Obesity and Diabetes: Sridevi Devaraj, Peera Hemarajata and James Versalovic; Clin Chem, 2013, 59(4): 617–628

Compositional and Functional Features of the Gastrointestinal Microbiome and Their Effects on Human Health: Emily B. Hollister, Chunxu Gao and James Versalovic; Gastroenterology, 2014, 146(6): 1449–1458

The Microbiome and Disease: Reviewing the links between the Oral Microbiome, Aging, and Alzheimer’s Disease: Deborah K. Shoemark and Shelley J. Allen; J Alzheimers Dis, 2015, 43(3):725-38

Dietary effects on human gut microbiome diversity: Zhenjiang Xu and Rob Knight; Br J Nutr, 2015, 113, S1–S5

Gut microbiome composition is associated with temperament during early childhood: Christian LM, Galley JD, Hade EM, Schoppe-Sullivan S, Kamp Dush C and Bailey MT; Brain Behav Immun, 2015, 45:118-27

Investigation of the Association Between the Fecal Microbiota and Breast Cancer in Postmenopausal Women: a Population-Based Case-Control Pilot Study: James J. Goedert, Gieira Jones, Xing Hua, Xia Xu, Guoqin Yu, Roberto Flores, Roni T. Falk, Mitchell H. Gail, Jianxin Shi, Jacques Ravel and Heather Spencer Feigelson; J Natl Cancer Inst, 2015, 1;107(8)

Bone mineral density and nutrition

Bone mineral density and dietary patterns in older adults: the Framingham Osteoporosis Study: Katherine L Tucker, Honglei Chen, Marian T Hannan, L Adrienne Cupples, Peter WF Wilson, David Felson, and Douglas P Kiel; Am J Clin Nutr, 2002, 76:245–52

Calcium, vitamin D, milk consumption, and hip fractures: a prospective study among postmenopausal women: Diane Feskanich, Walter C Willett, and Graham A Colditz; Am J Clin Nutr, 2003, 77:504–11

Milk and acid-base balance: proposed hypothesis versus scientific evidence. Fenton TR and Lyon AW; J Am Coll Nutr, 2011, 30(5 Suppl 1):471S-5S

Milk Consumption During Teenage Years and Risk of Hip Fractures in Older Adults: Diane Feskanich, Heike A Bischoff-Ferrari, Lindsay Frazier and Walter C. Willett; JAMA Pediatr, 2014, 168(1): 54–60

Childhood obesity

Childhood obesity: behavioral aberration or biochemical drive? Reinterpreting the First Law of Thermodynamics: Robert H Lustig; Nat Clin Pract Endocrinol Metab, 2006, 2, 447-458

Increasing Healthy Eating vs. Reducing High Energy-dense Foods to Treat Pediatric Obesity: Leonard H. Epstein, Rocco A. Paluch, Meghan D. Beecher and James N. Roemmich; Obesity (Silver Spring), 2008, 16(2): 318–326

Metabolic impact of a ketogenic diet compared to a hypocaloric diet in obese children and adolescents: Ioanna Partsalaki, Alexia Karvela and Bessie E. Spiliotis; J Pediatr Endocrinol Metab, 2012, 25:7-8, 697–704

Consuming a hypocaloric high fat low carbohydrate diet for 12 weeks lowers C-reactive protein, and raises serum adiponectin and high density lipoprotein-cholesterol in obese subjects: Megan R. Ruth, Ava M. Port, Mitali Shah, Ashley C. Bourland, Nawfal W. Istfan, Kerrie P. Nelson, Noyan Gokce and Caroline M. Apovian; Metabolism, 2013, 62(12)

A New Biomarker of Hedonic Eating? A Preliminary Investigation of Cortisol and Nausea Responses to Acute Opioid Blockade: Jennifer Daubenmier, Robert H. Lustig, Frederick M. Hecht, Jean Kristeller, Josh Woolley, Tanja Adam, Mary Dallman and Elissa Epel; Appetite, 2014, 74: 92-100

Health and dietary 

Dietary Factors, Hormesis and Health: Mark P. Mattson; Ageing Res Rev, 2008, 7(1): 43–48

Fructose: It’s “Alcohol Without the Buzz" Robert H. Lustig; Adv Nutr, 2013, 4: 226–235

Diet-induced obesity in ad libitum-fed mice: food texture overrides the effect of macronutrient composition: Charles Desmarchelier, Tobias Ludwig, Ronny Scheundel, Nadine Rink, Bernhard L. Bader, Martin Klingenspor and Hannelore Daniel; British Journal of Nutrition, 2013, 109, 1518–1527

Primary Prevention of Cardiovascular Disease with a Mediterranean Diet: PREDIMED Study Investigators; N Engl J Med, 2013, 368:1279-90

Beyond Meatless, the Health Effects of Vegan Diets: Findings from the Adventist Cohorts: Lap Tai Le and Joan Sabaté; Nutrients, 2014, 6, 2131-2147

Non-caloric artificial sweeteners and the microbiome: findings and challenges: Suez J, Korem T, Zilberman-Schapira G, Segal E, Elinav E; Gut Microbes, 2015, 6(2):149-55

Neurodegenerative diseases and nutrition

The role of nutrition in Alzheimer’s disease: epidemiological evidence: M. C. Morris; Eur J Neurol, 2009, 16(Suppl 1): 1–7

Short-term fasting induces profound neuronal autophagy: Mehrdad Alirezaei, Christopher C. Kemball, Claudia T. Flynn, Malcolm R. Wood, J. Lindsay Whitton and William B. Kiosses; Autophagy, 2010, 6:6, 702-710

Nutrition and Alzheimer's disease: the detrimental role of a high carbohydrate diet: Seneff S, Wainwright G, Mascitelli L; Eur J Intern Med, 2011, 22(2):134-40

Integrative neurobiology of metabolic diseases, neuroinflammation, and neurodegeneration: Gertjan van Dijk, Steffen van Heijningen, Aaffien C. Reijne, Csaba Nyakas, Eddy A. van der Zee and Ulrich L. M. Eisel; Front Neurosci, 2015, 9:173

Diet, nutrients and metabolism: cogs in the wheel driving Alzheimer's disease pathology? Rhona Creegan, Wendy Hunt, Alexandra McManusa and Stephanie R. Rainey-Smith; Br J Nutr, 2015, 113(10):1499-517

Obesity and infertility in women

The relationship between gut and adipose hormones, and reproduction: Alexander N. Comninos, Channa N. Jayasena, and Waljit S. Dhillo; Hum Reprod Update, 2014, Vol.20, No.2 pp. 153–174

Female obesity and infertility: Talmor A and Dunphy B; Best Pract Res Clin Obstet Gynaecol, 2015, 29(4):498-506

Obesity and erectile dysfunction

Mechanisms of obesity and related pathologies: Androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction: Abdulmaged M. Traish, Robert J. Feeley and Andre Guay; FEBS Journal, 2009, 276, 5755–5767 

How does obesity affect fertility in men - and what are the treatment options? Stokes VJ, Anderson RA and George JT; Clin Endocrinol (Oxf), 2015, 82(5):633-8

Sports and nutrition

Fat adaptation in well-trained athletes: effects on cell metabolism: Wee Kian Yeo, Andrew L. Carey, Louise Burke, Lawrence L. Spriet and John A. Hawley; Appl Physiol Nutr Metab, 2011, 36: 12–22

The effects of Ramadan intermittent fasting on athletic performance: recommendations for the maintenance of physical fitness. Chaouachi A, Leiper JB, Chtourou H, Aziz AR, Chamari K; J Sports Sci, 2012, 30 Suppl 1:S53-73

The Use of Carbohydrates During Exercise as an Ergogenic Aid: Naomi M. Cermak, Luc J. C. van Loon; Sports Med, 2013, 43(11):1139-55

Rethinking fat as a fuel for endurance exercise: Jeff S. Voleka, Timothy Noakesb and Stephen D. Phinneyc; Eur J Sport Sci, 2015;15(1):13-20